教育经历
- 2013-2019，taptap点点投注，taptap点点app官方网站，生物学，博士
工作经历
- 2019-2021，taptap点点投注，博士后
- 2022-至今，taptap点点投注，助理研究员
研究内容
- 细菌性病原微生物致病、免疫调控机制
- 细菌四型分泌系统效应蛋白与宿主互作的机制
承担项目
- 01 巴尔通体效应蛋白BepD激活SHP2促进IL-10分泌的机制
- 02 巴尔通体效应蛋白BepC诱导应力纤维形成机制研究
- 03 巴尔通体效应蛋白BepE抑制BepC诱导细胞片段化的机制 中国博士后基金会特别资助
- 04 巴尔通体效应蛋白BepC诱导细胞片段化的机制 中国博士后基金会面上项目
论文
- Wang, M., Guan, Q., Wang, C., Hu, L., Hu, X., Xu, M., ... & Yuan, C. (2024). Anchorage of bacterial effector at plasma membrane via selective phosphatidic acid binding to modulate host cell signaling. Plos Pathogens, 20(11), e1012694.
- Wang, C., Zhang, H., Fu, J., Wang, M., Cai, Y., Ding, T., ... & Yuan, C. (2021). Bartonella type IV secretion effector BepC induces stress fiber formation through activation of GEF-H1. PLoS Pathogens, 17(1), e1009065.
- Wang, C., Fu, J., Wang, M., Cai, Y., Hua, X., Du, Y., ... & Yuan, C. (2019). Bartonella quintana type IV secretion effector BepE‐induced selective autophagy by conjugation with K63 polyubiquitin chain. Cellular Microbiology, 21(4), e12984.
- Wang C, Yu D, Cui L, Hua X, Yuan C, Sun H, Liu Y. Rapid and real-time detection of Porcine Sapelovirus by reverse transcription loop-mediated isothermal amplification assay. Journal of virological methods. 2014 Jul 1;203:5-8.
- Wang C, Guo L, Yu D, Hua X, Yang Z, Yuan C, Cui L. HEV-ORF3 encoding phosphoprotein interacts with hepsin. Hepatitis monthly. 2014 Jan;14(1).
- Enhancing Antibacterial Activity of Glabridin by an Ultrasound-Triggerable Nanoformulation，Advanced Healthcare Materials，15:e05951，共同通讯，IF=10.59，Q1;
- Bacterial EPIYA/EPIYA-like effector motifs and host regulatory pY-SH2 logic: a sequence-informed three-layer convergence model，Frontiers in Cellular and Infection Microbiology，16:1915865，IF=5.5，Q1；
- Complete genome and phenotypic characterization of a feline-derived Bartonella henselae strain with enhanced endothelial interaction and immunomodulatory phenotypes，Comparative Immunology, Microbiology and Infectious Diseases，102496，IF=2.41, Q1