15
2025.10

【第六十九期】蜱媒疾病防控的新视角:以吸血机制为切入点

2025-10-15 12:40 ~ 14:00
农生学院B楼104会议室
活动介绍

报 告 人: 钟正伟 农生学院动物科学系 长聘教轨副教授

时    间:2025年10月15日 (星期三) 12:40-14:00

地    点: 农生学院B楼104会议室

主办单位:农生学院学科与科技办、农生学院青年教师联谊会

报告题目:

蜱媒疾病防控的新视角:以吸血机制为切入点

报告摘要: 

媒介昆虫通过刺血和吸血等取食行为从感染宿主中获得病原体并将其传播给其他健康宿主,从而引发虫媒动物传染病的大规模流行。蜱虫是主要的传播疾病媒介之一,全世界蜱虫超过950余种,蜱传病原体有220余种,而不同蜱虫传播病原体的机制又存在差异。因此,单一的研究某种蜱传病原体的疫苗或药物缺乏广谱性。对蜱虫吸血行为学及其生殖发育的机制解析,有助于广谱性的抗蜱虫繁殖的药物或者疫苗靶点的研发。

报告人简介:

钟正伟,长聘教轨副教授,课题组组长(独立PI),博士生导师。2022年博士毕业于复旦大学,2022-2025年在复旦大学生命科学学院开展博士后的研究。主要从事蜱媒生殖发育及其感染病原体的机制研究,近年来先后主持国家自然科学基金青年、中国科协青年人才托举工程,国际系统与应用蜱螨学会资助国际合作等项目,入选上海市超级博士后,获国际系统和应用蜱螨学会“温廷桓奖”,复旦大学优秀博士论文等奖励。以第一作者(含共同一作)身份在Cell Host & Microbe,Cell Reports和PLoS Pathogens等杂志期刊发表多篇论文,3篇文章被选为封面文章。

【所在学科研究组研究方向】:

1)蜱媒吸血行为的机制研究;
2)共生菌影响蜱媒感染病原体的分子机制;
3)蜱虫繁殖及蜱传疾病的防控应用。

【代表性著作】

1.Zhong Z, Zhong T, Peng Y, Zhou X, Wang Z, Tang H, Wang J*. Symbiont-regulated serotonin biosynthesis modulates tick feeding activity. Cell Host Microbe. 2021 Oct 13;29(10):1545-1557.e4.
2.Zhong Z#, Wang K#, Zhong T, Wang J*. Mitochondrial fission regulates midgut muscle assembly and tick feeding capacity. Cell Rep. 2025 Apr 22;44(4):115505.
3.Song X#, Zhong Z#, Gao L#, Weiss BL, Wang J*. Metabolic interactions between disease-transmitting vectors and their microbiota. Trends Parasitol. 2022 Aug;38(8):697-708.
4.Zhong Z#, Wang K#, Wang J*. Tick symbiosis. Curr Opin Insect Sci. 2024 Apr; 62:101163.
5.Xu Y#, Zhong Z#, Ren Y#, Ma L, Ye Z, Gao C, Wang J*, Li Y*. Antiviral RNA interference in disease vector (Asian longhorned) ticks. PLoS Pathog. 2021 Dec 3;17(12): e1010119.

 

ACADEMIC SALON (69)

SPEAKER: Zhengwei Zhong

Tenure-track Associate Professor, Department of Animal Science, SAB

TIME :12:40-14:00 Oct 15th, 2025 (Wed)

VENUE:Room 104, Building B, SAB

ORGANIZER:Office of Discipline and Science & Technology, SAB; 
Young Teachers Association, SAB

TITLE: 

A New Perspective on the Prevention and Control of Tick-Borne Diseases: Focusing on Feeding Mechanisms 

ABSTRACT:

Vectors such as arthropods acquire pathogens from infected hosts through biting and blood-feeding behaviors, and subsequently transmit these pathogens to healthy hosts, leading to large-scale outbreaks of vector-borne diseases. Ticks are one of the major disease vectors. Worldwide, there are over 950 tick species, and more than 220 tick-borne pathogens have been identified. The mechanisms by which different tick species transmit pathogens also vary. Therefore, vaccines or drugs targeting a single tick-borne pathogen often lack broad-spectrum efficacy. Understanding the blood-feeding behavior and the mechanisms of reproduction and development in ticks is crucial for the development of broadly effective drugs or vaccines targeting tick reproduction.

活动详情
2025-10-15 12:40 ~ 14:00 农生学院B楼104会议室
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